DISTURBED INTRACELLULAR FOLATE HOMEOSTASIS IMPAIRS AUTOPHAGIC FLUX AND INCREASES HEPATOCYTIC LIPID ACCUMULATION

Disturbed intracellular folate homeostasis impairs autophagic flux and increases hepatocytic lipid accumulation

Abstract Background Metabolic associated fatty liver disease (MAFLD), a prevalent liver disorder affecting one-third of the global population, encompasses a spectrum ranging from fatty liver to severe hepatic steatosis.Both genetic and lifestyle factors, particularly diet and nutrition, contribute to its etiology.Folate deficiency, a frequently enc

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Penitentiary system and education: a narrative about prison context, person deprived of liberty and educator training

This paper reflects on the course of education in the prison system, starting from the description of its standardization and the reflections that these rules bring to those involved in the challenge Collections of educating.For this, he comments on the processes of change that the person deprived of liberty goes through in the context of imprisonm

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Use of dual planar jets for the reduction of flow-induced noise

The planar jet has been proposed to reduce the flow-induced noise.However, the self-noise emission from a single planar jet is a limiting factor on the performance based characteristics of Sectional Sofas this technology.Therefore, this research paper reports an alternative dual planar jets geometry in an attempt to minimize the self-noise of the s

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